Background: Melatonin Receptor 1A is a G-protein coupled, 7-transmembrane receptor (GPCR family, subfamily melatonin) that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
Description: Rabbit polyclonal to Melatonin receptor 1A
Immunogen: KLH conjugated synthetic peptide derived from Melatonin receptor 1A
Specificity: ·Reacts with Human, Mouse, Pig, Dog, Guinea Pig and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 39 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
