Background: The Melatonin Receptor B gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. The gene product is an integral membrane protein which is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.
Description: Rabbit polyclonal to Melatonin receptor 1B
Immunogen: KLH conjugated synthetic peptide derived from Melatonin receptor 1B
Specificity: ·Reacts with Human, Mouse, Dog and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 40 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
