Background: HOXB8 is a member of the Antp homeobox family. It is a sequence specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior posterior axis during development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive compulsive spectrum disorder trichotillomania.
Description: Rabbit polyclonal to HOXB8
Immunogen: KLH conjugated synthetic peptide derived from HOXB8
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 28 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
