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Cystatin B antibody, 胱抑素B抗體

 
編 號 PR-3717
產品名稱 Cystatin B antibody, 胱抑素B抗體
規 格 0.2ml
價 格 1980元
應 用 IHC,WB,ELISA,ICC,IP,IF
品 牌 Hopebiot

詳細信息: 說明書下載

Background:   The Cystatin superfamily encompasses proteins that contain multiple Cystatin like sequences. Some of the members are active Cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 Cystatins (Stefins), type 2 Cystatins and Kininogens. Stefin B functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutated forms of this protein are responsible for the primary defects in patients with progressive myoclonic epilepsy.

Description: Rabbit polyclonal to Cystatin B

Immunogen: KLH conjugated synthetic peptide derived from Cystatin B

Specificity:  ·Reacts with Human, Mouse, Pig and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 14 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-500;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.

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