Background: Matrix Metalloproteinase 23 was first described in tumor cells. MMP23 shares much of the same domain structure as the classical MMPs, but has a unique cysteine array. The cysteine switch that is found in the classical MMPs is lacking or has a different sequence in MMP23. MMP23 has a furin cleavage site and it is thought to be localized within the cell. MMP23 has been reported as splice variants with different truncations at its C-terminus. MMP23 is predominantly expressed in ovary, testis, and prostate indicating that it plays a specialized role in reproductive processes.
Description: Rabbit polyclonal to MMP23
Immunogen: KLH conjugated synthetic peptide derived from MMP23
Specificity: ·Reacts with Human, Mouse and Rat.
.·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 44 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-500;
·Immunocytochemistry: 1/100-200;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
