Background: CYP27A1 is a member of the cytochrome P450 superfamily of enzymes. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. It catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. It also has also a vitamin D3-25-hydroxylase activity.
Description: Rabbit polyclonal to CYP27A1
Immunogen: KLH conjugated synthetic peptide derived from CYP27A1
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 60 kDa;
·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;
·Immunocytochemistry: 1/100-500;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
