Background: Citrulline is the deaminated form of arginine. Recently, the detection of citrillunated proteins, specifically keratin, has been of interest in the preliminary diagnosis of rheumatoid arthritis (RA). The epitope of keratin that is recognized by auto-antibodies is cyclic citrulline. Antibodies developed to recognize cyclic citrulline peptide (CCP) have provided earlier RA detection as compared to the historically used rheumatoid factor analysis.
Description: Rabbit polyclonal to CCP
Immunogen: KLH conjugated synthetic peptide derived from CCP
Specificity: ·Reacts with Cyclic Citrulline Peptide.
·Isotype: IgG
Application: ·Western blotting: 1/100-500;
·Immunohistochemistry (Frozen/paraffin tissue section): 1/50-200;
·Immunocytochemistry: 1/100;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
