Background: Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. [SUBCELLULAR LOCATION] Cell membrane; Multi-pass membrane protein. [TISSUE SPECIFICITY] Parietal cells, pancreas, brain and various neoplastic tissues. [SIMILARITY] Belongs to the G-protein coupled receptor 1 family.
Description: Rabbit polyclonal to Gastrin receptor
Immunogen: KLH conjugated synthetic peptide derived from Gastrin receptor
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 50 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
