Background: Malonyl-CoA decarboxylase(MLYCD) is an enzyme associated with Malonyl-CoA decarboxylase deficiency. It catalyzes the conversion of malonyl-CoA into acetyl-CoA and carbon dioxide. To some degree, it reverses the action of Acetyl-CoA carboxylase. The product of this gene catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency.
Description: Rabbit polyclonal to MLYCD
Immunogen: KLH conjugated synthetic peptide derived from MLYCD
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 55 kDa;
·Immunohistochemistry (Frozen/paraffin tissue section): 1/50-200;
·Immunocytochemistry: 1/100;
·Optimal working dilutions must be determined by the end user.
