Background: This protein promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. It can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). It appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Description: Rabbit polyclonal to Bad
Immunogen: KLH conjugated synthetic peptide derived from Bad
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 18 kDa;
·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;
·Immunocytochemistry: 1/100-500;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
