Background: Multidrug resistance-associated protein 1 (MRP1) is an ATP binding cassette (ABC) transporter, that confers resistance to many natural product chemotherapeutic agents and can transport structurally diverse conjugated organic anions. May participate directly in the active transport of drugs into subcellular organelles or influence drug distribution indirectly. Confers resistance to anticancer drugs. Transports LTC4. May protect milk against xenobiotics (By similarity). Subcellular location at Membrane; multi-pass membrane protein. Tissue specificity: Lung, testis and peripheral blood mononuclear cells. Belongs to the ABC transporter family. Conjugate transporter (TC 3.A.1.208) subfamily. multidrug resistance protein 1 (MRP1)
Description: Rabbit polyclonal to MRP1
Immunogen: KLH conjugated synthetic peptide derived from MRP1
Specificity: ·Reacts with Human, Mouse, Cow and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 171 kDa;
·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;
·Immunocytochemistry: 1/100-500;
·ELISA: 1/1000;
·Optimal working dilutions must be determined by the end user.
