Background: Stomatin is an integral membrane protein found in lipid/protein-rich microdomains of almost all human tissues. It was named after the rare human disease haemolytic anaemia hereditary stomatocytosis. Stomatin is implicated in signal transduction and cell communication, and it may regulate cation movement through ion channels and transporters. Absence of Stomatin may cause Na+ and K+ ions to leak into and from erythrocytes. A second function of Stomatin may be to act as a cytoskeletal anchor. Stomatin is a major lipid-raft component of erythrocytes and epithelial cells, and is also an abundant platelet protein. It contains a single hydrophobic domain, close to the N-terminus, and a phosphorylation site.
Description: Rabbit polyclonal to Stomatin
Immunogen: KLH conjugated synthetic peptide derived from Stomatin
Specificity: ·Reacts with Human, Mouse, Pig, Dog and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 32 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
