Background: Estrogen Receptor beta is a recent discovery, initially cloned and characterized from testis. Estrogen Receptor beta is highly homologous to Estrogen Receptor alpha; the ligand and DNA binding domains are highly conserved, while the amino terminus (transactivation domain), has diverged significantly. Estrogen Receptor beta binds estrogen with high affinity and regulates estrogen specific gene activation through direct interaction with estrogen response elements (EREs).
Description: Rabbit polyclonal to Estrogen Receptor β
Immunogen: KLH conjugated synthetic peptide derived from Estrogen Receptor β
Specificity: ·Reacts with Human, Mouse, Pig and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 59 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
