Background: Rab L3 (RAB-like protein 3) is a 236 amino acid protein that belongs to the small GTPase superfamily and the Rab family. A large family of small GTPases, Rab proteins play important roles in multiple processes relating to cellular transportation and modulation of the cytoskeleton. Rab L3 is considered a novel oncogene that regulates behavior or human cancer cells and may be a candidate for anti-tumor treatment. The Rab L3 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito and C.elegans, and maps to human chromosome 3q13.33. Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, Brugada syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Description: Rabbit polyclonal to RABL3
Immunogen: KLH conjugated synthetic peptide derived from RABL3
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 26 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
