Background: FAM38A, also designated Membrane protein induced by beta-amyloid treatment (Mib), is a 2,036 amino acid protein that is expressed in brain and may play a role in Alzheimer’s disease. The encoding FAM38A maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, a gastrointestinal inflammatory condition that may involve the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.
Description: Rabbit polyclonal to FAM38A
Immunogen: KLH conjugated synthetic peptide derived from FAM38A
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
