Background: Mouse macrophage galactose and N-acetylgalactosamine-specific lectin (mMGL), also designated macrophage asialoglycoprotein-binding protein (M-ASGP-BP) or macrophage galactose/N-acetylgalactosamine-specific lectin) is a protein with galactose-binding activity and with sugar-binding specificity that is the same as that of the native lectin. mMGL serves as a unique macrophage marker in mouse lung tissue due to its topographical site-dependent pattern of expression. Additionally, the most intense signal is observed in the extract from skin, suggesting that cells expressing this lectin are abundant in skin. mMGL may also participate in the binding of the macrophages to tumor cells. Cells which stain positively for mMGL are distributed in the connective tissue and in the interstice, particularly the dermis and subcutaneous layer of skin.
Description: Rabbit polyclonal to MMGL
Immunogen: KLH conjugated synthetic peptide derived from MMGL
Specificity: ·Reacts with Human, Mouse and Rat.
.·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 38 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
