Background: P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds. There are currently 57 known active cytochrome P450 (CYP) genes and 58 known pseudogenes present in the human genome. Several P450 enzymes have been classified by sequence similarities as members of the CYP1A and CYP2A subfamilies. CYP2U1 is a 544 amino acid protein that belongs to the CYP2 family of cytochrome P450 proteins. These proteins are usually involved in the metabolism of foreign compounds. CYP2U1 metabolizes arachidonic acid, docosahexaeonic acid and other long chain fatty acids. CYP2U1 may be involved in modulating the arachidonic acid signaling pathway in the cerebellum and thymus.
Description: Rabbit polyclonal to CYP2U1
Immunogen: KLH conjugated synthetic peptide derived from CYP2U1
Specificity: ·Reacts with Human, Mouse and Rat.
.·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 62 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.