Background: Chondrolectin, also known as transmembrane protein MT75 or CHODL, is an N-glycosylated, single pass type I membrane protein that localizes to the endoplasmic reticulum (ER)-Golgi apparatus. Chondrolectin contains one carbohydrate recognition (CRD) domain and is predominantly expressed in vascular muscle of testis, red pulp of spleen and smooth muscle of prostate. Chondrolectin is also found in heart muscle, skeletal muscle, and small intestine. Chondrolectin shares significant homology with the hyaluronan receptor, layilin, but does not appear to interact with hyaluronan. At least two other isoforms of Chondrolectin exist due to alternative splicing. They are soluble proteins and are designated CHODLÎE and CHODLfÎE. These isoforms may play an important role in T cell development.
Description: Rabbit polyclonal to CHODL
Immunogen: KLH conjugated synthetic peptide derived from CHODL
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 36 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
