Background: ORP150 (150KDa Oxygen-regulated Protein) is a member of the heat shock protein/stress protein family and has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. This protein has also been described as a molecular chaperone, induced by various environmental and physiological stimuli, and participates in protein folding in the endoplasmic reticulum. Furthermore, ORP150 is up-regulated in tumors and, in breast tumors, may be associated with tumor invasiveness.
Description: Rabbit polyclonal to ORP150
Immunogen: KLH conjugated synthetic peptide derived from ORP150
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 111 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
